What is tranexamic acid?

Tranexamic acid (TXA) started life as a medicine before dermatology discovered its remarkable effect on pigmentation. Rather than bleaching pigment that has already formed, TXA interrupts the conversation between melanocytes and their environment – with a soothing action on the vascular signals associated with melasma and post-inflammatory hyperpigmentation (PIH).

How it works

• Melanogenesis control – reduces melanocyte-keratinocyte interaction and promotes degradation of MITF, the master pigmentation switch.
• Vascular and soothing action – unique among brighteners, TXA also addresses the redness and vascular component of melasma.
• Used in mesotherapy – intradermal tranexamic microinjections are designed to help reduce the appearance of pigmentation associated with melasma, without notable side effects.

Fusion Meso formulations with tranexamic acid

• F-TRANEXAMIC – tranexamic acid sterile vials, the dedicated pigmentation protocol.
• F-MELACLEAR – TXA combined with niacinamide, resorcinol, glutathione and arbutin for localised dark spots.
• F-HA GLOW – hyaluronic skin booster with TXA and brightening peptide for global radiance.
• MELA DROPS – intensive home-care booster: TXA with hexylresorcinol, glycolic acid and niacinamide.
• GLOW SLEEPING MASK – overnight brightening with TXA and niacinamide.

Protocol notes for professionals

Tranexamic protocols are evaluated over 8-12 weeks and always paired with daily SPF50 – Fusion Meso MESO SHIELD 50 completes the routine. In-clinic vials address the pigment at its source; home boosters maintain the result between sessions. Professionals can combine it with the wider pigmentation vials for mesotherapy range.

Frequently asked questions

Is tranexamic acid suitable for all skin types?

Its non-aggressive mechanism makes it one of the best-tolerated pigmentation actives, including for darker phototypes prone to PIH – under professional guidance.

TXA or hydroquinone?

TXA is widely used in professional practice as a gentler-profile alternative to hydroquinone-based regimens for melasma-related concerns, which is why it has become a popular first-line choice.