Niacinamide, the universal support active

Niacinamide (vitamin B3) is the most versatile active in professional skincare: it strengthens the skin barrier, regulates sebum, evens tone and calms reactivity – all with outstanding tolerance. For clinics, that versatility makes it the ideal companion active: it prepares skin for procedures, supports recovery afterwards and makes stronger actives easier to tolerate.

What niacinamide does

• Barrier strength – documented ceramide synthesis boost (up to x2.9) and trans-epidermal water loss reduction (-27% documented).
• Tone and clarity – reduces melanin production in melanocytes, supporting anti-pigmentation protocols.
• Microbiome balance – targets C. acnes while sparing the beneficial skin flora.
• Tolerance partner – pairs with retinol and exfoliating acids to keep professional-strength routines comfortable.

Fusion Meso formulations with niacinamide

• F-NIACINAMIDE – sterile vials for radiant, even skin in professional protocols.
• NIACINAMIDE 5.0 – daily booster: USP niacinamide in olive squalane.
• F-MELACLEAR and MELA DROPS – pigmentation programmes where niacinamide supports the tranexamic strategy.
• F-ACN and ACN CORRECTOR – acne protocols combining niacinamide with zinc PCA.
• GLYCOLIC B3 FOAM – glycolic exfoliation balanced with vitamin B3.
• RADIANCE CREAM – niacinamide with hexylresorcinol for daily tone correction.
• GLOW SLEEPING MASK – overnight brightening with niacinamide and tranexamic acid.

Frequently asked questions

Can niacinamide be used right after a procedure?

Its excellent tolerance makes it one of the first actives reintroduced post-procedure, following the practitioner’s protocol.

Does niacinamide conflict with vitamin C?

No – the old incompatibility claim has been disproven at modern formulation standards; the two actives are complementary for radiance and tone.