Peptides in Aesthetic Medicine Skincare
What are peptides?
Peptides are short chains of amino acids – the language skin cells use to communicate. In professional skincare, specific peptide sequences are selected for precise biological messages: stimulate collagen, relax expression micro-contractions, drain, brighten or re-densify. Fusion Meso formulates with a broad library of well-characterised peptides, each chosen for a defined mechanism.
Fusion Meso formulations with peptides
- Acetyl Octapeptide-3 & Pentapeptide-18 – peptides that modulate acetylcholine release via the SNARE complex, in a mechanism similar to neuromodulator injectable treatments; designed to help soften the appearance of expression wrinkles and support the visible effect of neuromodulator injectable treatments. Found in F-BTX.
- Oligopeptide-24 – EGF-biomimetic peptide activating skin regeneration pathways; and Oligopeptide-34, a TGF-β1-mimetic that helps reduce the appearance of pigmentation. Both in F-LIFT+ FACE.
- Hexapeptide-10 – re-densifying peptide that reinforces the dermo-epidermal junction (laminin-5, α6-integrin). In F-LIFT+ FACE and F-EYE CONTOUR.
- Acetyl Hexapeptide-37 – hydration peptide that up-regulates aquaporin-3 water channels. The core of F-HYDRALIX.
- Acetyl Tetrapeptide-5 – anti-oedema peptide for under-eye bags and dark circles. In F-EYE CONTOUR and in F-EYE GLOW.
- Acetyl Tetrapeptide-40 – calms LL-37-driven redness in sensitive, rosacea-prone skin. In F-COUPERIX.
- Acetyl Tetrapeptide-3 with red clover extract – hair-anchoring peptide complex acting on 5-alpha-reductase, used to help support scalp health in cases of hair thinning. In F-HAIR MEN and HAIR MEN MIST.
- Copper Tripeptide-1 (GHK-Cu) – the regenerating copper peptide, covered in depth on our dedicated GHK-Cu page.
- Acetyl Glycyl Beta-Alanine – brightening peptide acting on melanogenesis enzymes and melanosome transfer. In F-HA GLOW and F-MELATRIX.
- Acetyl Hexapeptide-38 – volumising peptide (PGC-1α pathway) used for lips in F-PERFECT LIPS.
- Decapeptide-4 – IGF-1R pathway peptide supporting cell renewal, in F-HAIR MEN.
Peptides alongside professional treatments
Because peptides work by signalling, they pair naturally with procedures that stimulate the skin: mesotherapy, micro-needling and radiofrequency all increase the skin’s receptiveness to peptide messages. Clinics use Fusion Meso sterile serum vials in-procedure, then targeted home care between sessions.
Frequently asked questions
Do peptides replace injectables?
No – they complement them. Combining F-BTX with neuromodulator injectable treatments is designed to help support the visible results of those treatments.
How long before peptide skincare shows results?
Signalling takes time: most protocols are evaluated over 8-12 weeks of consistent use, ideally anchored to in-clinic sessions.