F-MELACLEAR is an outstanding treatment for dark spots. The product is formulated to be used on very localized facial areas. The main component of the formula is tranexamic acid. In the skin it inhibits UV-induced plasmin activity in keratinocytes by preventing the binding of plasminogen to the keratinocytes, which ultimately decreases melanocyte tyrosinase activity. Tranexamic acid is suitable to all kinds of skin for removing pigmentation, whitening skin and reducing spots. Nevertheless tranexamic acid does not directly affect the tyrosinase and to obtain the best results we combined it with safe and effective skin lightening ingredients like resorcinol, glutathione, niacinamide and arbutin. F-MELACLEAR requires the synergistic use of the Meso-shield 50 for a maximum and long-lasting result.