How to treat melasma with tranexamic acid?


Melasma, a common skin condition, causes dark, discolored patches that often appear on the face. The condition, which predominantly affects women, particularly during pregnancy or those on hormonal contraception, can be challenging to treat due to its propensity to recur. Tranexamic acid, traditionally used to control bleeding, has emerged as an effective ingredient in the treatment of melasma. Furthermore, when tranexamic acid is delivered through mesotherapy and micro-needling, it can significantly reduce the appearance of these stubborn pigmentation patches.

Tranexamic Acid: A Novel Approach to Treating Melasma

Tranexamic acid has anti-inflammatory, anti-angiogenic, and melanogenesis-inhibiting properties, making it an excellent candidate for melasma treatment. This works because it blocks the plasminogen/plasmin pathway, which, when activated, generally leads to increased melanin production. By inhibiting this pathway, tranexamic acid helps reduce melanin synthesis, leading to a lighter pigmentation over time.

Mesotherapy with Tranexamic Acid for Melasma

Mesotherapy involves the injection of small amounts of various pharmaceuticals, plant extracts, vitamins, and other ingredients directly into the skin.

1. Procedure:

– To treat melasma, inject a solution containing tranexamic acid into the skin’s mesodermal layer affected by hyperpigmentation.

– Use a fine needle to deliver multiple micro-injections across the melasma patches.

– The direct application ensures that high concentrations of tranexamic acid reach the target area, maximizing its efficacy.

2. Frequency:

– Treatment schedules vary, but a common regimen involves monthly sessions for a period determined by the healthcare provider, based on the severity of the melasma. Typically, you should use a product that has a concentration of 1%.

3. Benefits:

– Targeted application may result in a faster and more pronounced reduction in pigmentation.

– Minimal systemic absorption, reducing the risk of side effects compared to oral medication.

Micro-needling with Tranexamic Acid for Melasma

Micro-needling, also known as collagen induction therapy, creates micro-wounds in the skin using a device equipped with fine needles, which help deliver the tranexamic acid.

1. Procedure:

– Apply a topical formulation of tranexamic acid (1%) to the skin before or during the micro-needling process.

– The micro-wounds created by the needles enhance the absorption of tranexamic acid into the skin.

– The procedure also stimulates collagen production, aiding in skin repair and rejuvenation.

2. Frequency:

– You should typically space treatments 4-6 weeks apart, and the number of sessions will vary based on how the individual responds to the treatment.

3. Benefits:

– Micro-needling can improve skin texture and elasticity alongside the lightening of pigmentation.

– Combining this with other topical treatments can enhance results.

Combining Mesotherapy and Micro-needling for Enhanced Effect

Some people might be advised to use both mesotherapy and micro-needling to fight melasma in a stronger way.

– This two-step method makes sure the tranexamic acid goes deep into the skin and helps make more collagen, which could lead to better results.

Important Considerations

– Sun Protection: Rigorous sun protection is crucial when treating melasma, as UV exposure can worsen the condition.

– Professional Oversight: A trained skin doctor or a certified skin care expert should do these treatments in a safe clinic to lower any chances of problems.

Using tranexamic acid to treat melasma can be a good option for those dealing with this stubborn skin problem. Mesotherapy and micro-needling offer precise and careful ways to get this acid into the skin, which may greatly fade dark spots. With the right treatment approach and careful sunblock use, people with melasma can enjoy clearer, more balanced skin. It’s always important to talk with a skin doctor to pick the safest and best treatment for your skin type and issues.